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The hopes of the Earth ride on a great ship hurtling through no-space. Contact is maintained by Noelle and Yolanda, telepathic twins, one on Earth, the other aboard the ship. Then, fifteen light-years away, they start to lose their connection. It seems that this general scenario has been used elsewhere, but I can't think of it right off. (Heinlein's Time for the Stars
has been suggested by a well-read visitor.) This is a very enjoyable story with a grand, cosmic ending. It has now been expanded into the novel Starborne.
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